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American Cruise Lines

Baltimore Cruise Guide > Cruise Ships > American Cruise Line

American Cruises from Baltimore

American Cruise Lines offers coastal cruises on modern ships. The small ships are able to navigate America's smooth, inland waterways and dock in untraveled ports. American Cruise Line itineraries let you experience each area's local culture, history and natural beauty.

Take one of the American Cruise Line small ships on a cruise from Baltimore to the little towns of the Chesapeake Bay. Or sail down the east coast on the protected waters of the Intracoastal Waterway.

American's small ship cruises feature friendly all-American crew. Skilled chefs prepare feasts that highlight the flavors of the regions you'll visit. Enjoy complimentary cocktails and hors d'oeuvres before dinner. Dining is informal and you can sit with whomever you like. Each table has an outside view, so take your time and savor your cooked-to-order meal.

All staterooms face outside and are the largest in their class - featuring private baths and large, opening picture windows. Some staterooms also have private balconies.

Chesapeake Bay

7-night Chesapeake Bay cruises on American Cruise Lines. Round-trip from Baltimore to Yorktown (Virginia), Williamsburg (Virginia), St Michaels (Maryland) and Annapolis (Maryland).
• 2025 departures: May 3, May 10, May 17, June 2, October 6, October 13, October 20, October 27.
• 2026 departures: April 11, April 18, April 25, May 30, June 1, June 6, July 25, August 1, September 5, September 12, October 3, October 10.

Potomac River & Chesapeake Bay

7-night Potomac River & Chesapeake Bay cruises on American Cruise Lines. One-way from Baltimore to Washington (DC). Visit Annapolis (Maryland), St Michaels (Maryland), Cambridge (Maryland), Williamsburg (Virginia) and Mount Vernon (Virginia).
• 2026 departures: May 2, May 16, June 13, June 27, July 11, August 8, August 22, September 19, October 17.

East Coast

14-night East Coast Inland Passage cruise on American Cruise Lines. One-way from Baltimore to Amelia Island (Florida). Visit St Michaels (Maryland), Norfolk (Virginia), Kitty Hawk (North Carolina), Beaufort (North Carolina), Wilmington (North Carolina), Charleston (South Carolina), Beaufort (South Carolina), Hilton Head (South Carolina), Savannah (Georgia), St Simons Island (Georgia), Jekyll Island (Georgia) and Fernandina Beach (Florida).
• 2025 departures: October 31, November 1, November 7.
• 2026 departures: October 27, November 4, November 5.

American Cruise Lines
Chesapeake Bay Cruise
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